Faculty

CORE FACULTY

Eli Chapman, Ph.D., ,  Assistant Professor, Department of Pharmacology & Toxicology

 

Chris Hulme, Ph.D., Phil, Oxon.,  Professor, Department of Pharmacology & Toxicology
Discovery and development of novel anticancer therapeutics; high-throughput medicinal chemistry and the development of novel chemistries with iterative efficiency to expedite the drug discovery process.

Laurence H. Hurley, Ph.D., Purdue University, Professor, Department of Pharmacology & Toxicology
Discovery and development of novel anticancer drugs

Hong-yu Li, Ph.D., Associate Professor, Department of Pharmacology & Toxicology
Discovery and development of novel anticancer therapeutics; development of a novel fragment-based drug discovery approach and synthetic methodologies to expedite the drug discovery process.

Daekyu Sun, Ph.D., Assistant Professor, Department of Pharmacology & Toxicology
Discovery and development of novel anti-angiogenic agents targeting transcriptional activation of VEGF and HIF-1alpha genes; Study of the mechanism of action of novel anticancer agents derived from natural products: Investigation of DNA-repair interference as a potential approach for cancer treatment.

Georg T. Wondrak, Ph.D., Technical University Berlin, Germany, Associate Professor, Department of Pharmacology & Toxicology
Redox drug discovery targeting human skin cancer.

Danzhou Yang, Ph.D, University of Illinois, Professor,Department of Pharmacology & Toxicology
DNA and DNA interacting proteins as potential anticancer drug targets. Structure-based rational drug design.

ASSOCIATE FACULTY

Todd Camenisch, Associate Professor, PhD, Pharmacology & Toxicology
Investigating the integration between extracellular matrix and growth factor receptor signaling during heart morphogenesis.

Qin Chen, Professor, PhD, Pharmacology
Molecular mechanisms of oxidative injury and adaptation, stress signal transduction pathways, stress gene expression, senescence, apoptosis and cardiac hypertrophy.

Yin Chen Assistant professor, PhD, Pharmacology and Toxicology
Research interest is to understand the dysfunction of airway epithelium in the pathogenesis of a variety of acute and chronic airway diseases.

Nathan Cherrington, Professor, PhD, Pharmacology & Toxicology
Studying molecular mechanisms of hepatotoxicity during cholestasis and employing a functional genomics approach based on flexible small-scale arrays to measure the expression of xenobiotic transporter and drug metabolism genes.

Bernard W. Futscher, Professor, PhD, Pharmacology and Toxicology
Functional genomics; molecular biology of cancer; cancer pharmacology.

A. Jay Gandolfi, Professor Emeritus, PhD, Pharmacology and Toxicology
Bioactivation of xenobiotics: in vitro toxicology systems; renal/hepatic toxicology; toxicity of halogenated hydrocarbons, and metals; mechanisms cell injury.

Walter Klimecki, Associate Professor, PhD, Pharmacology and Toxicology
Associating human genetic backgrounds and diverse environmental exposures to understand individual variability in disease susceptibility.

Serrine Lau, Professor, PhD
Genomic and proteomic approaches to investigate ROS and chemical-induced cell injury and carcinogenicity; molecular mechanisms of prostanoid mediated cytoprotection; mass spectrometric application of protein profiling and tissue imaging.

R. Clark Lantz, Professor, PhD, Cell Biology and Anatomy
Pulmonary toxicology of air pollutants, especially metals; effects of air pollutants on neonatal lung growth and development

Terrence J. Monks, Professor, PhD, Pharmacology and Toxicology
Molecular mechanisms of chemical-induced toxicities; stress response pathways and apoptotic/oncotic cell death; ROS-induced DNA damage and chromatin structure/function.

John W. Regan, Professor, PhD, Pharmacology and Toxicology
Molecular pharmacology of G-protein coupled receptors: use of cloning, mutagenesis and expression to study receptor structure and the interaction of receptors with second messenger systems.

Catharine L. Smith, Associate Professor, PhD, Pharmacology and Toxicology
Epigenetic mechanisms of gene regulation, steroid receptor action in breast cancer, signal transduction and cell cycle control, mechanism of anti-cancer drug action.

Richard R. Vaillancourt, Associate Professor, PhD, Pharmacology and Toxicology
Molecular and biochemical characterization of serine/threonine protein kinases that function as part of sequential protein kinase pathways.

Donna Zhang, Professor, PhD, Pharmacology and Toxicology
The Nrf2/Keap1 signaling pathway that is activated by oxidative stress and chemopreventive compounds; Regulation of gene expression by the ubiquitination and proteasomal degradation pathway